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Its connection to glutathione, as drawn in the literature, runs through a cellular signalling pathway the Nrf2 system which researchers associate with the way cells regulate the expression of a family of antioxidant-related and stress-response genes, some of them involved in glutathione metabolism

The block of the dimerization, phosphorylation and DNA binding of TF leads to prolonged survival of SHH-MB PDX and GEM models and potentiates radiotherapy (RT) in vivo

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