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p=0.003) at 6-month follow-up in the 447 patients with unstable angina enrolled in the placebo arm of the CAPTURE trial.27 Hs-CRP concentrations increase rapidly after ACS, reaching a peak at 4896 hours, with a progressive return to baseline levels over the following weeks.41 The measurement of hs-CRP in the acute phase of an ACS may reflect the combination of the low-grade systemic inflammation that triggers the atherosclerotic plaque rupture and the inflammatory response secondary to myocardial ischaemia and necrosis.19 Patients with non-ST segment elevation MI tend to have more stable hs-CRP concentrations in the acute phase of the coronary condition, given the lower degree of inflammation after myocardial necrosis in these patients.42 The origin of the elevated hs-CRP levels in patients with ACS is unknown

Incorporation of antioxidants has been shown to further improve stability profiles of retinol-containing delivery systems

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