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The active cytosolic enzyme exists as a dimer of two subunits [3,4]
Defects in formation of FANCD2 nuclear foci after cisplatin treatment can be used to indicate cisplatin sensitivity [17] and concomitant overexpression of PARP1 , FANCD2 , and TP53 predicted increasing resistance to platinum [18]
Atli O, et al
elegans , suggesting that these pathways may be linked and that environmental contributors to neurodegenerative disease may proceed through pathways implicated in familial forms
Protein Nutrition and Mineral Absorption
