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The MDA level in the SCI group was significantly higher than that in both the control group ( P = 0.0002) and the GlyNAC+SCI group ( P = 0.0003)

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Collectively, these results suggested that APR-017 and LCS3 treatment induce vulnerability of VRK2-deficient PC cells by GSH inhibition and consequent disruption of the balance between ROS generation and antioxidation

Castellani S, et al

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