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These ABC transporter families, expressed in various tissues such as the liver, intestine, kidney, and brain, are divided into seven subfamilies (ABCA to ABCG) based on their gene structure, amino acid sequence, domain organization, and phylogenetic analysis

Gastroenterology 164 , 11801188.e1182 (2023)

Mechanistically, it influences gene networks involved in tissue remodeling and exerts protective antioxidant and anti-inflammatory actions, partly through TGF- signaling and regulation of metalloproteinases

Pharmacokinetic and pharmacodynamic modeling of MOD-4023, a long-acting human growth hormone, in growth hormone deficiency children

ACh - Acetylcholine