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NAM treatment increased mitochondrial NAD + /NADH ratios and improved mitochondrial membrane potential in human primary cells 115

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Unexpectedly, subjects receiving CNTF in clinical trials for this indication experienced weight losses of 10--15%, prompting researchers to consider using CNTF to treat obesity [71]

Available from: [DOI] [PMC free article] [PubMed] 61.Sikiric P, Ruman R, Turkovi B, Sever M, Klicek R, Radi B, et al