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and HMOX is a potent effector of the antioxidant defense system

Astrocytes-derived factors, such as MMP-2 and MMP-9, are able to enhance the migration and invasion of breast tumor cells, thus leading to brain metastasis (113)

HLA complexes were immunoprecipitated by incubating 40 L per 5 10 7 cells of GammaBind Plus Sepharose Beads (Cytiva, 17088601), pre-charged for 3 h, with 100 g per 5 10 7 cells of anti-human MHC Class I (HLA-A, HLA-B, HLA-C) antibody (clone W6/32, BioXCell, BE0079) and rotating overnight at 4 C