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If your vitamin B12 is part of a multivitamin containing iron or calcium, these minerals are well-known causes of constipation

For instance, tumor-derived vascular endothelial growth factor (VEGF) suppresses DC differentiation and maturation, while soluble Fas ligand can induce apoptosis in activated lymphocytes

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This is observed in people who undergo bariatric surgery where significant weight loss is accompanied by improvements in pulmonary function parameters such as FEV 1 , FVC, total lung capacity (TLC), and DLCO [84, 85]
