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Common side effects may include pain or redness at the injection site, mild diarrhea, or headaches [3]

These findings indicate that by inhibiting CD38 ectoenzyme, Ab68 boosts organismal NAD + levels, which promotes sirtuin activity, providing a potential mechanistic explanation for Ab68s anti-fibrotic effect in mice

J Clin Investig

SdAb#2F8 has favorable properties for RLT, such as high affinity for the CD38 antigen and lack of competition with daratumumab, making it a promising theranostic agent

On the other hand, modulating CD38 enzymatic activity may serve as a NAD boosting therapy for aging and metabolic diseases (Figure 1)[1-4, 6, 19, 36, 39]