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Previous studies have highlighted that, under deficit irrigation, strawberry plants exhibit leaf curling, chlorosis, reduced root and stem development, limiting nutrient transport, impaired respiratory and photosynthetic activities, enzymatic activities, hormonal balance and membrane functions, resulting in lipid peroxidation and chlorophyll degradation in plants and causing oxidative stress 8,9

Neeb H, Ermer V, Stocker T, Shah NJ

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Moreover, properly harnessing the Nrf2/HO-1 axis while managing its potential pro-ferroptotic risks may help maintain redox balance and curb iron overload, thereby offering an additional strategy to alleviate ferroptosis-driven damage in OA (202)

Zhexiang Fan, Qian Qu and Ruosi Chen collected the clinical samples