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Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium

Progesterone works as natures own 5-alpha reductase inhibitor (5-ARI)

Under hypoxic conditions, calcium (Ca 2+ ) and magnesium (Mg 2+ ) are key to preserving erythrocyte membrane deformability

You may experience a cluster (one-sided, severe, intensive, piercing pain), tension (mild to moderate, constant pain that feels like a tight band squeezing your head), or migraine (severe, pulsating pain that is usually one-sided) headache that usually develops either within 3 hours (immediate) or 512 hours after drinking

In collaboration with postdocs Tatiana Lima and Martin Minns, Karl helped identify a novel role for Pseudomonas aeruginosa exotoxin S ADP-ribosyltransferase activity in the activation of NLRP3 inflammasome in neutrophils