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Avoids Serious Complications In patients with severe anaemia, intensive treatment with B12 may result in a sudden drop in potassium (hypokalaemia), which can cause muscle weakness or an irregular heartbeat

2017 Oct 1;186:66-79

An increased delivery of fatty acids to skeletal muscle, as well as diminished mitochondrial oxidation, results in increased intracellular content of fatty acid metabolites such as diacylglycerol (DAG), fatty acyl-CoAs, and ceramides

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