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The antinociceptive effect of ALC is mediated by increases in the expression of metabotropic glutamate receptor 2 (mGlu2) in the regions of CNS connected with pain transmission via an epigenetic mechanism involving the acetylation of the p65/NFkB complex [26]
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doi: 10.1080/10408398.2011.578221 205 MetcalfRGJamesMJMantziorisEClelandLG
