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Also, oxaliplatin-induced mechanical hyperalgesia is reduced in germ-free mice and in mice pretreated with antibiotics, which further suggests that the gut microbiota promotes the development of oxaliplatin-induced mechanical hypersensitivity and neuroinflammation

A randomized cross-over trial in thirty-six MS patients with fatigue showed that 3 months of acetylcarnitine supplementation had a more favourable effect on fatigue severity than amantadine supplementation [131]

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in: PubMed | Google Scholar 1 Department of Cellular and Molecular Medicine, Lerner Research Institute, 2 Center for Microbiome and Human Health, and 3 Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA