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What is the purpose of epigenetics in the modulation of the expression of proteins belonging to the carnitine system

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While oral L-Carnitine supplements are widely available, they suffer from poor bioavailability, with the body absorbing as little as 1020% of the compound

In a subset analysis examining non-carriers of the APOE -e4 genotype, a genetic marker indicating increased susceptibility to Alzheimer disease, higher DHA concentrations or omega-3 index scores were associated with larger hippocampal volumes

However, not all interventions proved effective, as acetyl-L-carnitine plus alpha-lipoic acid failed to reverse insulin resistance in another NAFLD mouse model (32)