glutathione biosynthesis pathway enzymes Biosynthetic of Study proposes a new strategy

GSH is a low molecular weight (small)molecule that is called a tripeptide (three amino acids)

A small pilot study of women within 5 years of menopause given 2g NAC per day suggests it may reduce bone resorption, warranting larger trials

3.2 ABSORPTION AND DIFFERENCES BETWEEN PHYSIOLOGICAL AND PHARMACOLOGICAL DOSES The percentage of absorption decreases as the dose increases

(1) This peptide appears to be naturally present in the bloodstream and has been suggested as a potential element in regulating the growth, development, and apoptosis of vascular endothelial cells

(4) increased hepatic and renal urea cycle intermediates suggesting hypercatabolism and upregulation of the urea cycle independent of impaired renal clearance of nitrogenous waste