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High levels of IL-8, a strong chemoattractant for neutrophils, has been detected early in infected SARS patients.3 Once activated by infection, neutrophils are rapidly recruited to sites of inflammation in the lungs, where they produce and secrete cytokines, enzymes, including elastase (NE), reactive oxygen species (ROS) by oxidative burst, and finally release DNA to form neutrophil extracellular traps (NETs).4 In severe COVID-19 patients, an increased number of neutrophils has been associated with disease severity,5 most likely due to the production of large amounts of proinflammatory cytokines, creating a cytokine storm

doi: 10.3892/ol.2012.829 42 RomanASmeuALascuADeheleanCAPredescuIAMotocAet al

Sessions typically run 30 to 60 minutes, depending on the treatment selected

In instances of pernicious anaemia, bariatric surgery, severe malabsorption, inflammatory bowel disease involving the ileum, and substantial neuropsychiatric symptoms, vitamin B injections are highly recommended