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To summarize, CAFs and ECM within the TME influence the HGF/c-MET signaling pathway through their interactions with immune cells and the secretion of HGF, leading to the formation of an immunosuppressive TME that accelerates tumor growth

Not because hormones are the only factor, but because if your hormones are chaotic, nothing else will work optimally

Our rodent studies show that CAQK treatment results in a reduction in TnC expression in the injured brain, suggesting that TnC levels might be a potentially useful pharmacodynamic biomarker
