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Retatrutide extends the same class further as a triple receptor agonist, targeting the GLP-1, GIP, and glucagon receptors together, with the added glucagon activity aimed at boosting energy expenditure alongside appetite suppression
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The desensitization process is carried out according to a protocol that assumes a gradual increase in the drug dose until a therapeutic dose is reached, which is simultaneously associated with a gradual increase in the threshold concentration (which would cause anaphylaxis)
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