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The activation of PLC results in the release of inositol-1,4,5-trisphosphate (IP 3 ) from membrane associated phosphatidylinositol-4,5-bisphosphate (PIP 2 ), which then binds to specific IP 3 receptors in the endoplasmic reticulum/sarcoplasmic reticulum (ER/SR) resulting in the release of intracellular stores of Ca 2+

10.1007/s00253-016-7400-4 265 ShinD.ChoiW.BaeH

Neurol Sci 34(10):17911796 Kaneko Y, Nakayama T, Saito K, Morita A, Sato I, Maruyama A, Soma M, Takahashi T et al (2006) Relationship between the thromboxane A 2 receptor gene and susceptibility to cerebral infarction

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