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doi: 10.1002/adfm.201906950
I see them as teammates one defends, the other powers me forward
Kesawat MS, Satheesh N, Kherawat BS, Kumar A, Kim HU, Chung SM, et al
When the NLRP3 inflammasome is activated, it activates caspase-1, which then forms active forms of pro-inflammatory cytokines such as IL-1 and IL-18 [186]
The flexibility of that loop and the binding of a CS agent like verapamil could favor a particular conformation for the massive transport of GSH, not related to other transport activities of MRP1
