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glutathione pathway red blood cells Apoptosis and glutathione: beyond an antioxidant Mini MCAT passage: Pentose phosphate
Description
doi: 10.1038/nature14344 25 WangLLiuYDuTYangHLeiLGuoMet al

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Using erastin-treated A549 cells, we measured intracellular Fe 2+ , ROS, lipid peroxide, glutathione, glutamate release into the extracellular space, and cystine uptake

These endotoxins and PAMPs activate liver macrophages and Kupffer cells, increasing the production cytokines that are pro-inflammatory like TNF-, IL-6, and interleukin-1 beta (IL-1)

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