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By measuring the metabolic flux profile of Mtb in a macrophage model of TB, we discovered that in the absence of Rv1127c, metabolism was dysregulated, and its growth inhibited (Basu et al, 2018)

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Clinical pharmacokinetics of the antiandrogens and their efficacy in prostate cancer

Dermal fibroblasts from the patients generated markedly increased lipid-ROS compared to control cells, as assessed by BODIPY-C11 staining, suggesting that ferroptosis might also be activated in this context