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The molecular interaction analysis further highlighted the significance of Tyr-326 in aromatic interactions, along with the presence of a critical hydrogen bond with Cys-172, essential for anchoring MAO-B inhibitors

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Acute treatment with 9 -THC or synthetic CB1 agonists produce well-characterized signs of intoxication and anti-nociception in humans and laboratory animals through CB1 activation (Wiley and Martin, 2003)

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