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Description
These early clinical studies were paralleled by experimental studies in rodent models

These findings highlight the therapeutic potential of L

Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)
The perception of B12 shots as 'energy boosters' largely stems from the dramatic improvement seen when treating genuine deficiency, where fatigue is a cardinal symptom

Importantly, none of the tested substances improved all the cognitive abilities assessed, but only certain specific aspects
