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Description
Studies have shown that ferritin in the brain increases with age (Belaidi et al., 2018), which is positively correlated with cognitive dysfunction
Therefore, the presence (or the production) of oxidative metabolites will stimulate the pathway (transsulfuration) that will eventually result in their neutralization

Moreover, excessive Fe 2+ overload would further feed back into apoptosis by inducing ER stress and activating pro-apoptotic pathway (28), which ultimately worsen metabolic dysfunction and liver injury

Evaluation of the effects of mulberry leaf extracts Morus alba L

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