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For example, hypervitaminosis A can be caused by taking one large dose of over 200 mg of vitamin A, or chronic use of more than 10 times the recommended daily intake ( Vitamin A toxicity may lead to serious complications, such as increased spinal fluid pressure, coma, and potentially fatal organ damage ( Additionally, taking megadoses of vitamin D more than 50,000 IU daily over long periods can lead to high blood levels of calcium (hypercalcemia), which can lead to death ( Overdosing on other vitamins can likewise cause potentially fatal side effects, such as liver damage

doi: 10.1016/j.mce.2021.111206 20 BouillonR

Health professionals recommend testing B12 levels regularly for early detection of deficiencies

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Getting better data on what TAK-101 does to symptoms with gluten exposure over the long term is a key thing we're going to need to study in the near future, Leffler said