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Exercise also counts, but it's not what REALLY moves the needle
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In lipopolysaccharide (LPS)-exposed primary mouse lung endothelial cells, MAPK kinase 3 (MKK3) deficiency activated PGC--regulated mitobiogenesis and Parkin/PINK1-regulated mitophagy concurrently, resulting in a healthy mitochondrial network and protection against sepsis [208]
This can cause those medications to be ineffective
