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Description
J Clin Investig

Based on the modeled PDZD-8 structure, we hypothesized that changing leucine-98 and isoleucine-252 of the PDZD-8 SMP domain to tryptophan (W) would block lipid insertion into its hydrophobic groove (Supplementary Fig

10.1002/pmic.201700300 Proteomics Summary Keywords carnitine, biosynthesis, biosensor, metabolic engineering, biosynthetic cascade, trimethyllysine Citation Kugler P, Trumm M, Frese M and Wendisch VF (2021) L-Carnitine Production Through Biosensor-Guided Construction of the Neurospora crassa Biosynthesis Pathway in Escherichia coli

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