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Rev Analg 2003;7:14563.Article 3

L-Ornithine HCl: We included Ornithine to support energy consumption efficiency and promote the excretion of ammonia

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Quantification of the synergy using multidimensional synergy of combinations (MuSyC) 37 technique for AXT050 and sorafenib at steady state suggest an inconsequential synergistic efficacy ( obs = 0.001 and 0.035 for pAkt and pERK, respectively), as well as a negligible antagonistic potency (log( 2 ) = 0.02 and 0.05 for pAkt and pERK, respectively)