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SARS-CoV-2 suppresses mRNA expression of selenoproteins associated with ferroptosis, endoplasmic reticulum stress and DNA synthesis

2023b), Fig

This structural damage causes further mitochondrial failure and even more ROS leakage, creating a continuous "doom loop" of profound energy depletion, systemic inflammation, and the hallmark symptom of post-exertional malaise (PEM)
