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The repeated NAD + /NADH conversions also suggest much more complicated and repeated oxidation/reduction responses in brain cortex during neuronal and astrocytic activities than previously considered (e.g., Kasischke et al., 2004)

Teng Xu and colleagues identified that, in head and neck squamous cell carcinoma (HNSCC), the DLG motif within tumor necrosis factor--induced protein 2 (TNFAIP2) competes with the Kelch domain of Keap1, thereby inhibiting the ubiquitin-proteasome-mediated degradation of NRF2

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anemia characterized by anisocytosis and RBC lipo-peroxidation leading to increased RBC fragility [32,33] thrombocytopenia and leucopenia [4,34]

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