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Currently, an ongoing clinical trial is evaluating the effects of simvastatin in patients with uterine fibroids (IRB Number: IRB00149869)

Allergy-wise, the risk is very low

It is also important to consider that the identification of cell types responsible for Fc-dependent antibody-mediated protection in mice (and other animal models) does not necessarily translate directly to humans owing to factors including differences in the FcR expression profile of these cells (Table 1) and differences in the relative abundance of these cell types in tissues and in circulation

Wen H, Yang HJ, An YJ, et al

Nemati H, Ghahramani M-H, Faridi-Majidi R, Izadi B, Bahrami G, Madani S-H, Tavoosidana G