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Description
Glutathione exists in a reduced (GSH) and an oxidised (GSSG) form, and the GSH/GSSG ratio is a widely used research marker of cellular redox state
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Therefore, therapeutic strategies that manipulate ROS levels, either by increasing oxidative stress to promote cell death or by targeting antioxidant pathways to inhibit tumor growth, are being explored 118
W., Ezenwa M
Elevated levels of ROS can lead to oxidative damage to cellular components, including lipids, proteins, and DNA
