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The only responsible conclusion is that oncological safety is unproven
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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Li J., Li X., Liu E., Copeland P., Freudenreich O., Goff D.C., Henderson D.C., Song X., Fan X
Disadvantages involve benefit decline during off periods requiring acceptance of fluctuation, complexity planning and tracking cycles, uncertainty about optimal timing and duration for individual responses, and potential for forgetting to restart after extended breaks
