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In 1986, a group of doctors wrote in an article: This group (of 41 chronically ill patients) had somatization disorder diagnosed by specific criteria

For instance, an inverse relationship was described between the chlorambucil effect and GSH levels and activity [119,120] or between GSH levels and the concentration of cyclophosphamide active metabolites, suggesting a possible decrease in their efficacy during anticancer treatments [121]

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Smoking was also a strong predictor for the association between vitamin B6 and B12 and methylation for several multi-disease-related gene promoters in humans [67]

At an acidic pH, propeptide elimination can happen auto- or trans-catalytically (Pritsch et al., 2020