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Methylglyoxal, whose formation can reach 3 mg/kg body weight/day [230], is a glycating agent, forming mainly arginine-derived hydroimidazolone adducts, DNA adducts, and isomeric imidazopurinones [231]
Candidalysin: discovery and function in Candida albicans infections
591 Genes involved in the generation of the carbon core taxadiene ( 90 ) (taxadiene synthase), hydroxylation of the skeleton at C 5 , C 13 , C 10 , C 2 and C 7 , as well as downstream acylation steps have been characterized and reconstituted in various hosts (Figures 73 and 74)
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Rats received AOD 9604 daily for 6 months and cynomolgus monkeys for 9 months
