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Clinical Evidence: No IGF-1 Changes Human clinical trials measured serum IGF-1 levels at baseline and throughout treatment with AOD-9604 at various doses
Research found that supplementation with a range of Lactobacillus types improved kidney function, reduced inflammation and reversed leaky gut in female mice (x)
Then, once a week for four more weeks

Combined nicotinamide N-methyltransferase inhibition and lean-diet substitution reduces body weight and liver fat in obese mice
