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Thus, treatment of LNCaP cells with the DNA demethylating agent 5-azacytidine also restored activating histone modifications on GSTP1 and as a result reactivated transcription
These data confirm the important role of TREK-1 and TRAAK in CIPN [82, 83]
Co-supplementation of VD+LC in mice resulted in elevated NRF2, increasing the antioxidant enzymes and improving the cellular glutathione levels
Am J Physiol Gastrointest Liver Physiol 300(6):G948-55, 2011
This effect was enabled by activating the p75NTR and TrkA receptors and the upstream MAP/ERK signaling pathway
