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Causes and Risk Factors Genetics is an important contributor in up to 90% of cases, with a variant gene HLA-Cw6 conferring the greatest risk There are also many triggers including injury, sunburn, infection, obesity, certain medications, emotional stress, alcohol, and tobacco Signs and Symptoms While psoriasis can appear anywhere on the skin, it most often affects the elbows, knees, scalp, lower back, and genitals

Life Sci 281:119754 Hassanein EH, Althagafy HS, Atwa AM, Kozman MR, El-Sayed MIK, Soubh AA (2022) Taurine attenuated methotrexate-induced intestinal injury by regulating NF-B/iNOS and Keap1/Nrf2/HO-1 signals

DG conceptualized the study and revised the manuscript

High doses can lead to systemic spillover, desensitization, and increased side effects like hypoglycemia or swelling

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