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Challenges such as healthcare infrastructure, cost of biomarker testing, and access to high-quality supplements further complicate the implementation of precision supplementation strategies in these settings

Vegans had levels above the reference range for alanine, glutamate, glycine, leucine, ornithine (a non-protein amino acid), phenylalanine, and serine
Currently, according to two consecutive nationwide epidemiological surveys in reproductive-aged women in China, the prevalence of PCOS has increased by nearly 65% from a decade ago, and a weighted prevalence under the Rotterdam criteria reached 7.8% (95% CI 7.0%, 9.0%) in 2020 [7]

The American Journal of Tropical Medicine and Hygiene , 96 (3), 686691

eCollection 2018 Zamani P, Rawat D, Shiva-Kumar P, Geraci S, Bhuva R, Konda P, Doulias PT, Ischiropoulos H, Townsend RR, Margulies KB, Cappola TP, Poole DC, Chirinos JA
