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Besides, significantly greater CSF levels of transforming growth factor 1 (TGF-1), IL-1, and IL-6 were also observed in PD patients than those in controls, according to a systematic study of CSF cytokines in PD patients ( 3.5.2 C-reactive protein (CRP) The degree of raised CRP levels in CSF has been reported to be strongly correlated with the severity of non-motor symptoms in PD patients

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Sekiyama K.D., Yoshiba M., Thomson A.W

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