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The proposed model based on mutagenesis and structural analyses suggests that alcohol stabilizes the open conformation of GIRK channels by displacing amino acids in the closed state, particularly at the base of the alcohol pocket ( FIGURE 4 In a study employing an alcohol tagging approach with GIRK2, He et al., 2002

Endotoxin testing (LAL test): For any application involving live cell systems, endotoxin levels must be assessed via the Limulus Amebocyte Lysate (LAL) test

Enzyme-based presence-absence tests detect total coliform and E

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