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This combination triggered a weight loss of 14.5% in a phase 1 trial of 110 people with obesity [77]
When a random set of parameters is generated, we then examined the generated set of initial parameters and whether they are confined to a steady state of metabolic flux for 24 hours before the glucose administration using the experimentally measured molecule concentrations as the initial values

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& Krakauer, J

PMID 18459613
