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, Smith G

doi:10.1016/j.blre.2012.03.002 Eelderink C, Kremer D, Riphagen IJ, et al

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Notably, some of the source studies in Table 1 did provide full FICI indices using checkerboard assays (Not mentioned in the table as most studies have no FICI)

Knockdown of NLRP3 or caspase-1 reduced neuronal death and reversed cognitive impairments [147], whereas PARP-1 -/- mice were observed to prevent synaptic damage, cognitive dysfunction, and microglial activation in an AD mouse model referring to the significant role of pyroptosis and parthanathos in the pathogenesis of AD [148, 149]