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In addition, the cell surface translocation of Glut1 and the glutamine transporters sodium-coupled neutral amino acid transporter (SNAT)1

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The recently developed mouse models of tumor-specific chromosomal transloctions (Forster 2005), BRCA1-associated breast cancer (Drost 2009), and preinvasive/invasive ductal pancreatic cancer described by David Tuveson and Tyler Jacks (Hingorani 2003) highlight both the utility and elegant complexities of these compound conditional lines of mice to replicate human disease

Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins

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