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SW480 and Caco-2 human colon cancer cell lines were obtained from the American Type Culture Collection (Manassas, VA, USA)

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Thiaminase is destroyed by heat, so make sure to boil horsetail for at least 5 minutes if you do choose to take it

Sustained inflammatory insults induce cumulative DNA damage and epigenetic reprogramming, fostering malignant transformation through two synergistic mechanisms: (1) persistent immune cell activation (neutrophils, macrophages, lymphocytes) and (2) tumor co-option of inflammatory mediators (IL-6, TNF-, COX-2) as metastatic accelerants