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Pollution causes depletion of skin surface antioxidant Vitamin E Vitamin E is the main antioxidant present at the surface of the skin that protects it from the damaging effect of free radicals

Vitamin C Vitamin C is a potent antioxidant due to its high electron-donating capacity (Reference Padayatty, Katz and Wang128)

[DOI] [PubMed] [Google Scholar] 72.Dose J., Matsugo S., Yokokawa H., Koshida Y., Okazaki S., Seidel U., Eggersdorfer M., Rimbach G., Esatbeyoglu T

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In addition, some inducers of these enzymes affect phase I detoxification enzymes, which frequently may transform procarcinogens to actual carcinogens via metabolic activation by hydroxylases such as cytochrome P450