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Oxidative stress reduction mechanisms Antioxidant enzyme upregulation: BPC-157 increases superoxide dismutase (SOD), catalase, and glutathione peroxidase expression

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Malnutrition or malabsorption causes decreased insulin signaling which reduces GHR expression and blocks the GH signaling pathway leading to IGF-I expression (GHR uncoupling), while GHs metabolic actions on lipolysis and gluconeogenesis are unaffected