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GH exerts autocrine/paracrine effects by binding to GHR in the same or a neighboring cell surface and initiating JAK2- and SRC-mediated signaling cascades, which decrease pro-apoptotic molecules (Bax and PPAR) and suppress caspase protein activation (Figure 4A)
Microbial genes, brain & behaviourEpigenetic regulation of the gut-brain axis
It also reflects pathogenic processes, assesses treatment and intervention results, and identifies a physiologically homogeneous cohort of ASD patients (16)
, Rong P., Yang Y., et al
